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Altered expression of Cyp26a1 and Wnt3a in Gdf11−/− embryos. Whole-mount in situ hybridization on E9.5 and E10.5 of WT (A–F) and Gdf11−/− (G–L) embryos using antisense-Cyp26a1, -Wnt3a, and –Fgf8 probes. Insets are the magnified views of the PSM/tailbud area. Note the reduced expression of Cyp26a1 and Wnt3a in the tail bud (arrowhead) regions of Gdf11−/− embryos.
