Table 3.
GSH/GSSG Ratio
| GSH (μ mol/gm tissue) | GSSG (μ mol/gm tissue) | Ratio | |
|---|---|---|---|
| Control | 32.12 ± 2.6 | 11.3 ± 0.71 | 0.84 |
| CCl4 treated | 16.7 ± 1.05 | 19.6 ± 1.11 | -1.14 |
| Natansnin treated | 30.03 ± 2.4 | 11.5 ± 0.85 | 0.65 |
| Natansnin (10 mg) + CCl4 treated | 26.8 ± 1.7 | 14.7 ± 0.9 | -0.16 |
| Natansnin (20 mg) + CCl4 treated | 28.1 ± 1.91 | 14.1 ± 0.81 | -0.007 |
Reduced and oxidized glutathione levels were measured in liver homogenate from control, CCl4 and natansnin (10 mg/kg, 20 mg/kg body weight) treated rats. Glutathione levels are expressed as μmoles per gram tissue. Ratio = GSH-2(GSSG)/GSSG.