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PIST binds to cadherin 23 via its PDZ domain, as well as the CC2-plus region. A. Schematic diagram of chicken and human PIST domain structures, and the domains of human PIST used in co-IP experiments. B. EGFP-tagged PIST CC2-plus region is co-IPed with Myc-tagged cadherin 23(-68), but not cadherin 23(+68). C. EGFP-tagged PIST PDZ domain is co-IPed with Myc-tagged cadherin 23(+68) and cadherin 23(-68)
