Table 3.

Univariate analysis of prognostic factors of the patients (n = 60)

Variable	Unfavorable factor	Hazard ratio (HR)	95% CI of HR	p-value
LN	positive	12.1940	5.9509 to 24.9867	< 0.0001
Depth of invasion	pT3/4	3.8447	1.5309 to 9.6553	< 0.0001
Grading	High (G3/4)	4.0652	1.7123 to 9.6514	< 0.0001
MMP-1 expression	High (≥ 46%)	1.4526	0.7101 to 2.9718	0.3070

LN, Lymph nodes metastasis