. 2010 Oct 12;11:508. doi: 10.1186/1471-2105-11-508

Table 2.

Synonymous and non-synonymous analysis of mutations in the heterogeneity sites

Chrom Position	Types of Mutations	Genotype at SRX007711	Genotype at FPR3757	Alignment with Orthologous Proteins			Gene and Function
				`gi 87161249 ref`	`423`	`EKDATIEKSNTG`
						`E DATIEKSNTG`
						`ENDATIEKSNTG`
				`SRR022865_26088`	`1`	`gaggaagataag`
778416	NONSYN	T:6 G:140	G:37			`aaacctaacacg`
						`attattgaacat`	sulfatase family protein lipoate-protein ligase A family protein

1021087				`Query: 36 VKLAMEEYVLKN`	`1`
	NONSYN	T:5 G:151	G:37	`+ LAMEEYVLKN`
				`Sbjct: 14 LNLAMEEYVLKN`	`25`

				`gi 87162345 ref`	`143`	`AGIGRYLLNRVD`
						`AGIGRYLLNR+D`
						`AGIGRYLLNRLD`
				`SRR022865_32431`	`-37`	`Ggagattcaatg`	lantibiotic epidermin biosynthesis protein EpiC
						`Cgtggattagta`
1950547	NONSYN	A:5 C:164	C:37			`Tgagatgataat`

				`gi 87160275 ref`	`122`	`NCLPVYKILLEK`
						`NCLPVYKILL+K`
						`NCLPVYKILLKK`
				`SRR022865_59666`	`-36`	`attcgtaattaa`	Lactose phosphotransferase system repressor phosphotransferase system, glucose-specific IIABC component
						`agtctaatttaa`
2333470	NONSYN	T:5 C:164	C:37			`ttgggtatgaaa`

				`Query: 36 LV*IAPWLKNDI`	`1`
				`LV IAPWLKNDI`
2674216	TRUNC	A:5 C:170	C:37	`Sbjct: 41 LVEIAPWLKNDI`	`52`

				`gi 87161394 ref`	`71`	`KKVLLTGLGIVI`
						`KK+LLTGLGIVI`
						`KKLLLTGLGIVI`
				`SRR022865_30969`	`1`	`aatctagtgaga`
2648343	NONSYN	A:5 C:192	C:37			`aatttcgtgttt`	drug transporter

						`aaatagagaaac`
				`gi 87160343 ref`	`120`	`EVQSKEMLIISI`
						`EVQSKEMLI+SI`
						`EVQSKEMLIVSI`
				`SRR022865_47009`	`2`	`ggctagatagaa`
2262790	NONSYN	A:153 G:6	A:37			`atacaattttgt`	cation efflux family protein

						`ataaaagacttt`
				`gi 87160156 ref`	`825`	`SDSDSDSDSDSD`
						`SDSDSDSDSDSD`
						`SDSDSDSDSDSD`
				`SRR022865_28556`	`-37`	`agtgtgagtgtg`
861340	SYN	A:9 C:136	C:49			`gacacagacaca`	clumping factor A
						`ctatatctatac`

				`gi 87160605 ref`	`4`	`FTQLSDRIKKAI`
						`FTQLSDRIKK I`
						`FTQLSDRIKKDI`
				`SRR022865_49291`	`-36`	`tactagaaaaga`
1542366	NONSYN	A:14 G:85	G:37			`tcatgagtaaat`	hypothetical protein
						`ttagttacaacc`

				`gi 87160966 ref`	`476`	`RNDMVEFFGEKL`	5-
						`RN+MVEFFGEKL`
						`RNEMVEFFGEKL`	Methyltetrahydropteroyltriglut amate--homocysteine S- Methyltransferase
				`SRR022865_53088`	`1`	`cagaggttggat`
						`gaattattgaat`
408863	NONSYN	T:6 G:160	G:37			`ttagtaccaaaa`

				`gi 87161941 ref`	`177`	`VDVLDVYSDAY`
						`VD+LDVYSDAY`
						`VDLLDVYSDAY`
				`SRR022865_54601`	`3`	`ggttggttggt`
1180638	NONSYN	T:5 G:97	G:37			`tattatacaca`	cell division protein ftsA
						`ttaattcttat`

				`gi 87160920 ref`	`104`	`KGDIIGYVEAMK`
						`KGDIIGYVEA+K`
						`KGDIIGYVEAIK`
				`SRR022865_82913`	`-37`	`aggaagtgggaa`	acetyl-CoA carboxylase, biotin carboxyl carrier protein
						`agattgatacta`
1714319	NONSYN	T:6 C:95	C:37			`gattaattagaa`

				`gi 87162179 ref`	`415`	`AKSEVWRQMMSD`
						`AKSEVWRQM+SD`
						`AKSEVWRQMISD`
				`SRR022865_51952`	`-36`	`gaaggtccaatg`
						`cagatggattca`
2638027	NONSYN	A:5 C:112	C:36			`gataagtagtat`	gluconate kinase

				`gi 87161981 ref`	`47`	`DIAVVDIMMDGM`
						`DIAVVDIMMD M`
						`DIAVVDIMMDVM`
				`SRR022865_55616`	`-36`	`gaggggaaagga`
						`atcttatttatt`
2481059	NONSYN	T:5 G:148	G:37			`ttagattggttg`	response regulator protein

				`gi 87161886 ref`	`196`	`KSENIEKTVNRF`
						`K ENIEKTVNRF`
						`KIENIEKTVNRF`
				`SRR022865_56405`	`1`	`aagaagaagact`
						`ataataactagt`	thiamine-phosphate pyrophosphorylase
2212436	NONSYN	A:5 C:107	C:37			`atattagtttac`

				`gi 87161325 ref`	`64`	`PVVKELKKHAK`
						`P VKELKKHAK`
						`PFVKELKKHAK`
				`SRR022865_71442`	`3`	`ctgagtaacga`
						`cttaataaaca`
1252956	NONSYN	T:9 G:125	G:37			`ttaaagaataa`	DNA topoisomerase I

				`gi 87162241 ref`	`319`	`SMDNVVTVGSTD`
						`SM NVVTVGSTD`
						`SMYNVVTVGSTD`	lantibiotic epidermin leader
				`SRR022865_97728`	`2`	tataggaggtag
1948255	NONSYN	A:5 C:169	C:37			ctaattctgcca	peptide processing serine
						`tgctctaaatat`	protease EpiP

1309034	TRUNC	C:115 G:5	C:37	`Query: 35 ASAGKKSSI*N`	`3 ^b`		DNA mismatch repair protein MutS
				`Sbjct: 754 ASAGKKSSISN`	`764`

				`gi 87161934 ref`	`619`	`QQANVELSPTSD`
						`Q+ANVELSPTSD`
						`QKANVELSPTSD`
				`SRR022865_10478`	`2`	`cagaggtacatg`
950365	NONSYN	A:5 C:113	C:37			`aacatatgccca`
						`ggttcgataaat`	exonuclease RexB

				`Query: 1 FK*YFKQFEENY`	`36`
				`FK YFKQFEENY`
				`Sbjct: 223 FKSYFKQFEENY`	`234`
2512836	TRUNC	C:7 G:115	G:37				sensor histidine kinase

				`Query: 3 Q*IINDEVDIG`	`35`
				`Q IINDEVDIG`			LysR family transcriptional regulator
2678195	TRUNC	A:5 G:92	G:37	`Sbjct: 137 QQIINDEVDIG`	`147`

Note. TRUNC: truncated protein; NONSYN: non-synonymous mutation and SYN: synonymous mutation. ^a: align with Genewisedb and ^b: align with Blastx.