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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Acta Biomater. 2010 Aug 3;7(1):268–277. doi: 10.1016/j.actbio.2010.07.036

Table II.

Estimates of K½ for adsorption and desorption after the use of three different EDC cross-linking protocols for immobilizing PVPA within the EDC-cross-linked collagen matrices

Cross-linking Protocol Bmax Bmax/2 Estimate of K½ 95% CI (K½) Approx. S.E.
Adsorption EDC only 192.04 96.02 7093.05 6825.44–7370.45 136.25
EDC/NHS 193.72 96.86 7446.02 7006.28–7894.16 221.97
EDC/Im 216.12 108.06 8289.98 7906.74–8683.97 194.31

Desorption EDC only 144.45 72.22 6532.98 6272.24–6799.09 131.71
EDC/NHS 125.70 62.85 7455.93 7062.41–7865.60 200.80
EDC/Im 128.83 64.41 6134.97 5958.37–6306.35 86.99

Abbreviations: EDC = carbodiimide; NHS = N-hydroxysuccinimide; Im = imidazole