Skip to main content
. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Gastroenterology. 2010 Aug 1;139(5):1730–1739.e1. doi: 10.1053/j.gastro.2010.07.046

Figure 5. Impact of clofibrate treatment on stress signaling in MCD-fed mice.

Figure 5

(A) Mice were fed MCS or MCD formulas with or without 0.5% (w/w) clofibrate for 14 days. Liver sections were stained with hematoxylin and eosin. (B) Stress signaling was assessed by Western blotting in the livers of mice fed MCS and MCD formulas with or without clofibrate for 14 days. (C) The hepatic triglyceride content of mice fed diets with or without clofibrate was assayed as outlined in Methods. Biochemical and histologic parameters of liver injury were also measured at 14 days (n = 10). * P < 0.05 for MCD vs. MCS; ‡ P < 0.05 for MCD vs. MCD + clofibrate.