Figure 3.
BES1-mediated recruitment of elongation factors and histone-modifying proteins. BES1 not only binds histone-modifying proteins ELF6 and REF6 in the promoters of BR-responsive genes to initiate their transcription, most likely through demethylating histone H3 and altering chromatin structure, but also recruits elongation factors to the phosphorylated C-terminal domain (CTD-P) of the RNA polymerase II (RNAPII) within the transcribed regions of BR-regulated genes to promote the production and export of their mRNAs.
