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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Gastroenterology. 2010 Jul 1;139(5):1686–1698.e6. doi: 10.1053/j.gastro.2010.06.060

Figure 2.

Figure 2

Effect of transfection of CAT2 siRNA on H. pylori-stimulated iNOS expression and NO production. RAW 264.7 cells were transiently transfected with either scrambled siRNA or siRNA to CAT2. (A) mRNA expression assessed by RT-PCR at 6 h after stimulation with HPL. (B) Western blot analysis at 24 h after stimulation. In A and B, n = 3. (C) L-Arg uptake and (D) NO2− levels, measured 24 h after stimulation. **P < .01 vs control macrophages transfected with scrambled siRNA; §§P < .01 vs HPL-stimulated macrophages transfected with scrambled siRNA, n = 6. Scr, scrambled.