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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Eur J Pharmacol. 2010 Sep 18;649(1-3):51–58. doi: 10.1016/j.ejphar.2010.08.057

Fig. 2.

Fig. 2

Antagonistic effects of flavonoids genistein and apigenin. (A) H157 and H460 cells were treated with NSC-741909 alone or with 10 μM of U0126 or 1μM of CI1040 0.5 h before NSC-741909 treatment. Then, the dose response to NSC-741909 was determined after 48 h. (B) H157 and H460 cells were treated with NSC-741909 alone or with 10 μM genistein or apigenin 0.5 h before NSC-741909 treatment. Again, the dose response to NSC-741909 was determined after 48 h. The effects of the MEK inhibitors or flavonoids alone were presented at the data points when NSC-741909 was 0.