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. 2002 Sep 1;22(17):7434–7443. doi: 10.1523/JNEUROSCI.22-17-07434.2002

Fig. 4.

Fig. 4.

A, EPSPs in response to trains of stimuli at different frequencies are shown (left). EPSPs predicted by a simple model of depletion and facilitation in response to the same train are shown also (right). EPSPs and model EPSPs were scaled to the same peak amplitude for the first EPSP in the train. Scale bar is 300 msec for traces at 20 and 10 Hz, 640 msec for traces at 2 Hz, and 1.1 sec for traces at 1 Hz.B, The late component of the EPSPs during the train at 10 Hz is shown at a higher gain (black trace), along with the response predicted by the model (gray trace). The model, using parameters defined by the early component, accurately predicted the behavior of the late component, indicating that short-term plasticity is similar for AMPARs and KARs.C, There is a strong correlation between the EPSP amplitudes predicted by the model and the measured EPSP amplitudes. The model accounted for 75% of the total variability in EPSP amplitude during stimulus trains over a wide range of frequencies.