Fig. 5.
A, AMPAR-mediated (left) and KAR-mediated (right) EPSPs were modeled in response to a single afferent fiber firing randomly at the indicated frequency. Neither response generated a depolarization exceeding 2 mV over 20 sec of simulated firing. B, The average peak depolarization for a fiber over the 20 sec of the simulation is shown (n = 50 fibers) for AMPARs (filled circles) and KARs (open circles). C, The mean depolarization under the same conditions as B is shown for AMPARs (filled circles) and KARs (open circles).
