Table 3.
Low/not low model
| Gene | Name | P-Value |
|---|---|---|
| UBE3A | E6AP ubiquitin-protein ligase | 5.39E-05 |
| VKORC1 | Vitamin K1 2,3-epoxide reductase subunit 1 | 1.16E-04 |
| SLA2 | Src-like adapter protein 2 | 2.11E-03 |
| DICER1 | Dicer1, Dcr-1 homolog | 3.76E-03 |
| CYP2C9 | cytochrome P450, family 2, subfamily C | 5.49E-03 |
| SLC22A1 | solute carrier family 22 | 1.12E-02 |
| BBC3 | BCL2 binding component 3 | 1.49E-02 |
| F8 | Procoagulant component | 1.74E-02 |
| HMOX2 | heme oxygenase (decycling) 2 | 1.79E-02 |
| MUTED | muted homolog | 1.99E-02 |
| VWF | coagulation factor VIII VWF | 2.40E-02 |
| HSD3B7 | 3-beta-HSD VII | 2.56E-02 |
| SPIN1 | spindlin 1 | 2.58E-02 |
| SELPLG | selectin P ligand | 2.89E-02 |
| FAM113B | family with sequence similarity 113, member B | 2.92E-02 |
| F13B | Fibrin-stabilizing factor B subunit | 3.36E-02 |
| MVP | major vault protein | 3.39E-02 |
| UGT2B7 | UDP glucuronosyltransferase 2B7 | 3.83E-02 |
| AKR7A2 | aflatoxin beta1 aldehyde reductase | 4.17E-02 |
| SERTAD1 | CDK4-binding protein p34SEI | 4.96E-02 |
Top 20 genes with candidate gene-scores that significantly distinguish between low dose patients and non-low-dose patients (p≤0.05). P-Values are result of t test between low-dose and non-low-dose distributions of gene-scores. Genes in bold are significant after correcting for multiple hypothesis testing.