. Author manuscript; available in PMC: 2011 Nov 3.

Published in final edited form as: J Am Chem Soc. 2010 Nov 3;132(43):15192–15203. doi: 10.1021/ja106688j

Table 4.

Test for Non-linear Effects in the [COP-OAc]₂-Catalyzed Allylic Esterification^a

entry	cat. ee (%)^b	product ee (%)^c	ee_calc (%)^d
1	0	−2	0
2	20	15	16
3	40	34	34
4	60	52	53
5	80	75	71
6	>99	90	90

1 equiv 1 (R = Bn), 3 equiv PhCO₂H, 1 mol % 4, substrate concentration = 0.5 M.

Produced by mixing solutions of opposite enantiomer catalyst of >99% ee.

Determined by enantioselective SFC.

Calculated as straight line between 0% ee catalyst and 100% ee catalyst (ee_calc = ee₀·ee_cat, where ee₀ is product ee when ee_cat = 100%, i.e. 90 %)