FIG. 5.

Cerebral edema was not significantly affected by administration of 2.2 g/kg of glucose 15 min before injury. (A) Schematic timeline of the edema experiment. (B) Administration of this dose of glucose to rats significantly raised blood glucose prior to injury. Two days later, this level had returned to normal. (C) At 48 h post-injury, there was no significant difference in the level of cerebral edema between animals with elevated glucose at the time of injury and injured vehicle animals (n = 8/group). The dotted line represents the average level of brain water content previously observed in uninjured animals (data are presented as mean ± standard error of the mean; *p < 0.05).