Table 1.

Metastases observation developed in the hamster orthotopic pancreatic carcinoma model. Animals presenting pancreatic tumors were treated twice with DTA-H19 or Luc-H19 plasmids. Before each treatment, abdominal cavity was searched for metastases in both groups, the treated group DTA-H19 (n = 9) and the control group (n = 7). Most metastases appeared visible on day 9.

Group	Animals with metastasis on day 7/total	Animals with metastasis on day 9/total	Animals with metastasis on day 11/total
DTA-H19	0/9	3/9	3/9 Metastases in liver, stomach, or intestine (n≤ 2)
Luc-H19 (control group)	1/7	4/7	7/7 Multiple abdominal metastases (n> 3)