Figure 6.

Effect of 18 nt HYB0504 on expression of TS protein in RKO cells. Cells were incubated in the absence (lane 1) or presence of Eufectin–ORN complexes (9:1 ratio, µg:µg) for 3 h, grown for an additional 24 h and then harvested and processed for western blot analysis as described in Materials and Methods. Lanes 2–5 were treated with complexes containing 53, 106, 159 and 212 nM HYB0504, respectively.