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. 2010 Jul 26;3(2):272–276. doi: 10.1159/000319150

Table 1.

Hematologie parameters at baseline and following treatment changes

Baseline
Hydroxy-urea
Hydroxyurea/interferon
On copy drug (imatinib-COPER)
At discontinuation of copy drug
After starting imatinib (Glivec)
May 2002 July 2002 (2 months on hydrox urea) Nov2002 (4 months on f- hydroxyurea/IFN) Sept 13, 2006 (day before starting treatment) Nov 21,2006 (2 months after treatment) Dec 2008 Dec 20, 2008 Mar 23, 2009 May 6, 2009
Red blood cell count, ×106n/mm3 3.51 3.90 3.91 2.95 4.01 3.25 3.42 3.41 3.61
Monocytes, % 10.7 12.4 12.4 12.4 13.8 11.1 11.7 11.9 13.2
Total leukocyte count, n/mm3 207,000 3,000 11,000 13,500 8,000 90,690 54,000 6,980 7,530
Neutrophils, % 56 52 70 62 69 45 58 64 54
Eosinophils, % 1 2 2 2 4 1 1 7 1
Basophils, % 1 0 0 0 0 0 1 4 0
Lymphocytes, % 8 45 23 15 26 4 7 1.6 41
Monocytes, % 2 1 5 2 1 3 0 8 4
Platelet count, n/mm3 unknown 87,000 53,000 239,000 172,000 175,000 162,000 85,000 85,000

Myelemy 42% 4%
Myeloblasts 18% 100% − 100% − 47% 100% −
Myelocytes 17% no more myelemy no more myelemy 8% no more myelemy
Metamyelocytes 7% 11%