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Caloric intake after i.c.v. leptin. Rats maintained on CH (a) or KD (b) were injected into the lateral ventricle with saline or leptin. Caloric intake was measured 24 h after injection. For both dietary groups, caloric intake was significantly decreased 24 h after i.c.v. administration of 15 μg leptin. * p < 0.05 when intake was compared to intake following saline administration.
