Figure 4.
FBCRHOEdev mice show increased anxiety-like behavior. A–D, In the open-field test, FBCRHOEdev (n = 11) mice show increased latency to enter the center of the open field (A), decreased time in the center of the open field (B), decreased number of entries center of the open field (C), and decreased distance traveled in the center of the open field compared with controldev mice (n = 11) (D). E, FBCRHOEdev show equivalent total distance traveled in open-field testing compared with controldev mice. F–H, In the L:D preference task, FBCRHOEdev mice (n = 11) show increased latency to enter the light (F), decreased number of entries into the light (G), and decreased time in the light compared with controldev mice (n = 11) (H). Student's t test; *p ≤ 0.05; **p ≤ 0.01 compared with controldev mice.