Figure 2.

Characterization of the infiltrating cells in chondritic ear of NOD.DQ8 mice at 3 weeks and 8 weeks after onset of disease. At 3 weeks, CD4⁺, B220⁺, and Mac-1⁺ cells were seen in abundance distributed throughout the section. Eight weeks after onset of chondritis, infiltrating CD4⁺, CD8⁺, and Mac-1⁺ cells were reduced. B cells were present in aggregates, giving an appearance of follicles.