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. Author manuscript; available in PMC: 2010 Nov 2.
Published in final edited form as: Am J Med Genet A. 2006 Apr 1;140(7):785–789. doi: 10.1002/ajmg.a.31142

TABLE II.

PEMT Val75Ile Genotype and Risk of Spina Bifida

Genotype Cases (%) Controls (%) OR (95% CI)
Overall
 Val75/Val75 146 (41.7) 234 (41.3) Referent
 Val75/Ile75 158 (45.1) 250 (44.2) 1.01a (0.76, 1.35)
 Ile75/Ile75 46 (13.1) 82 (14.5) 0.90a (0.59, 1.36)
Non-Hispanic white
 Val75/Val75 38 (29.2) 78 (27.6) Referent
 Val75/Ile75 65 (50.0) 148 (52.3) 0.90 (0.56, 1.46)
 Ile75/Ile75 27 (20.8) 57 (20.1) 0.97 (0.53, 1.77)
Hispanic white
 Val75/Val75 88 (50.0) 104 (51.2) Referent
 Val75/Ile75 75 (42.6) 77 (37.9) 1.15 (0.75, 1.76)
 Ile75/Ile75 13 (7.4) 22 (10.8) 0.69 (0.33, 1.47)
a

Odds ratio adjusted to ethnicity group.