Table 3.
PRKACA (rs729372) Genotyping Frequencies among NTD Cases and Controls
| Case (%) | Control (%) | OR | 95% CI | |
|---|---|---|---|---|
| Overall | ||||
| CC | 135 (67.5) | 141 (70.1) | Reference | |
| CA | 56 (28.0) | 53 (26.4) | 1.1* | 0.7–1.7a |
| AA | 9 (4.5) | 7 (3.5) | 1.3* | 0.5–3.7a |
| Non-Hispanic white | ||||
| CC | 54 (79.4) | 60 (75.9) | Reference | |
| CA | 13 (19.1) | 17 (21.5) | 0.8 | 0.4–1.9 |
| AA | 1 (1.5) | 2 (2.5) | — | |
| Hispanic white | ||||
| CC | 58 (50.9) | 43 (53.8) | Reference | |
| CA | 46 (40.4) | 32 (40.0) | 1.1 | 0.6–1.9 |
| AA | 10 (8.8) | 5 (6.3) | 1.5 | 0.5–4.7 |
a
Adjusted for ethnicity group.
OR, odds ratio; CI, confidence interval.