Table 5.
PRKACB 3′-UTR (rs600674) Genotyping Frequencies among NTD Cases and Controls
| Case (%) | Control (%) | OR | 95% CI | |
|---|---|---|---|---|
| Overall | ||||
| CC | 136 (66.3) | 137 (67.8) | Reference | |
| CT | 56 (27.3) | 52 (25.7) | 1.1a | 0.7–1.7a |
| TT | 13 (6.3) | 13 (6.4) | 1.0a | 0.5–2.3a |
| Non-Hispanic white | ||||
| CC | 49 (74.2) | 55 (68.8) | Reference | |
| CT | 15 (22.7) | 21 (26.3) | 0.8 | 0.4–1.7 |
| TT | 2 (3.0) | 4 (5.0) | — | — |
| Hispanic white | ||||
| CC | 69 (62.7) | 58 (72.5) | Reference | |
| CT | 33 (30.0) | 19 (23.8) | 1.5 | 0.8–2.8 |
| TT | 8 (7.3) | 3 (3.8) | — | — |
a
Adjusted for ethnicity group.
OR, odds ratio; CI, confidence interval.