Table 2. Receiver-operator characteristics for proteins with predictive value for living in a BU endemic area.
Antigen | AUCa | 95% CI | Cut-off | Sensitivity (%) | Specificity (%) | Likelihood ratiob | NPVc |
MUP045 | 0.810 | 0.720–0.901 | 0.824 | 57.1 | 90.0 | 5.7 | 0.61 |
MUP057 | 0.753 | 0.652–0.854 | 0.893 | 39.7 | 93.5 | 6.2 | 0.57 |
MUL_0513 | 0.873 | 0.799–0.946 | 0.622 | 74.6 | 86.7 | 5.6 | 0.70 |
Hsp65 | 0.932 | 0.873–0.991 | 0.693 | 84.1 | 93.3 | 12.6 | 0.77 |
AT propionate | 0.897 | 0.832–0.962 | 0.896 | 79.4 | 86.7 | 6.0 | 0.70 |
KR A | 0.856 | 0.777–0.934 | 0.850 | 69.8 | 83.3 | 4.2 | 0.68 |
AUC, area under curve;
Likelihood ratio represents the likelihood that someone with a positive test will live in a BU endemic area, i.e. a likelihood ratio of 5.0 means someone with a positive test is 5 times more likely live in BU endemic area than an individual with a negative test;
NPV, negative predictive value.