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. 2010 Nov 2;4(11):e877. doi: 10.1371/journal.pntd.0000877

Table 1. Factors associated with death from visceral leishmaniasis in children (univariate and multivariate analysis).

Variable Dead(57)n(%) Alive(489)n(%) OR(95% CI) Adjusted OR (95% CI)
Clinical/demographic
Male sex 20(35) 255(52) 0.53 (0.3–1.0)
Age <5 years old 47(82) 323(66) 3.19 (1.4–7.5)
Severely malnourished* 8(14) 41(8) 1.78 (0.7–4.2)
Diarrhea 11(19) 62(13) 1.73 (0.8–3.7)
Edema 27(47) 69(14) 5.87 (3.1–11.1)
Jaundice 16(28) 22(5) 8.71 (3.9–19.1) 4.4 (1.7–11.2)
Dyspnea 24(42) 61(13) 5.43 (2.8–10.3) 2.8 (1.2–6.1)
Mucosal bleeding 10(17) 10(2) 10.69 (3.7–28.2) 4.1 (1.3–13.4)
Cutaneous bleeding 18(32) 31(6) 6.82 (3.3–14.0)
Upper gastrointestinal bleeding 4(7) 1(0.2) 38.27 (-)
Associated infections 23(40) 56(11) 5.56 (2.9–10.7) 2.7 (1.2–6.1)
Laboratory
Total leukocyte count<2,500/mm3 21(37) 142(29) 1.41 (0.8–2.6)
Total platelet count<50,000/mm3 43(75) 90(18) 15.01 (7.3–31.4) 11.7 (5.4–25.1)
Neutrophil count<500/mm3 17(30) 66(14) 2.68 (1.4–5.2) 3.1 (1.4–6.9)
Hemoglobin <5 g/dL 31(54) 103(21) 4.43 (2.4–8.1)

*Weight not available for 2 children.

†: Full blood count missing for 3children.