Table 3. Cell cycle genes up-regulated1 through PAR2 activation by either 2f-LIGRLO-NH2 or Trypsin.
| Name | Gene | 2f-O2 1.5h | 2f-O 3h | 2f-O 6h | 2f-O 12h | Trypsin3 6h |
| ARP1 actin-related protein 1 homolog A, centractin alpha | ACTR1A | 1.2 | 1.1 | 1.1 | 1.2 | 1.4 |
| cyclin A1 | CCNA1 | 1.3 | 1.9 | 1.7 | 1.3 | 2.1 |
| cyclin Y-like 1 | CCNYL1 | 1.2 | 1.3 | 1.1 | 1.1 | 1.5 |
| cell division cycle 123 homolog | CDC123 | 1.1 | 1.2 | 1.1 | 1.3 | 1.5 |
| cell division cycle 25 homolog A | CDC25A | 2.0 | 1.7 | 1.4 | 1.1 | 1.0 |
| dual specificity phosphatase 1 | DUSP1 | 1.4 | 1.6 | 1.3 | 1.1 | 1.3 |
| dual specificity phosphatase 6 | DUSP6 | 2.3 | 2.6 | 2.0 | 1.4 | 7.5 |
| fumarate hydratase | FH | 1.1 | 1.2 | 1.2 | 2.0 | 1.7 |
| FBJ murine osteosarcoma viral oncogene homolog B | FOSB | 1.6 | 1.3 | 1.0 | 1.0 | 1.1 |
| growth arrest and DNA-damage-inducible, alpha | GADD45A | 1.4 | 1.3 | 1.1 | 1.1 | 1.4 |
| general transcription factor IIH, polypeptide 1 | GTF2H1 | 1.7 | 1.7 | 1.3 | 1.3 | 1.1 |
| interleukin 8 | IL8 | 2.4 | 1.9 | 1.3 | 2.8 | 4.5 |
| v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | KRAS | 1.9 | 2.1 | 1.3 | 1.4 | 1.2 |
| nucleolar and coiled-body phosphoprotein 1 | NOLC1 | 1.9 | 1.8 | 1.7 | 1.6 | 1.3 |
| oxidative stress induced growth inhibitor family member 2 | OSGIN2 | 1.1 | 1.3 | 1.3 | 1.2 | 1.5 |
| PCTAIRE protein kinase 2 | PCTK2 | 1.2 | 2.0 | 1.0 | 1.3 | 1.4 |
| protein phosphatase 2 (formerly 2A), alpha isoform | PPP2CA | 1.3 | 1.5 | 1.2 | 1.2 | 1.2 |
| protein phosphatase 2 (formerly 2A), beta isoform | PPP2CB | 1.2 | 1.5 | 1.2 | 1.3 | 1.3 |
| protein tyrosine phosphatase type IVA, member 1 | PTP4A1 | 1.5 | 1.6 | 1.2 | 1.1 | 1.3 |
| SERTA domain containing 1 | SERTAD1 | 2.3 | 1.9 | 1.3 | 1.2 | 2.0 |
| seven in absentia homolog 1 | SIAH1 | 1.2 | 1.7 | 1.0 | 1.2 | 1.3 |
| structural maintenance of chromosomes 3 | SMC3 | 1.5 | 1.7 | 1.3 | 1.2 | 1.0 |
| TAF1 RNA polymerase II | TAF1 | 1.4 | 1.4 | 1.2 | 1.2 | 1.1 |
| transcription factor Dp-1 | TFDP1 | 1.1 | 1.2 | 1.3 | 1.4 | 1.2 |
| topoisomerase (DNA) III alpha | TOP3A | 2.3 | 1.5 | 1.4 | 1.2 | 1.2 |
| U2AF homology motif (UHM) kinase 1 | UHMK1 | 1.2 | 1.4 | 1.1 | 1.2 | 1.5 |
1Expression level expressed as fold differences of control (control = 1.0).
22f-O: 2f-LIGRLO-NH2 1 µM .
3Trypsin: Human Trypsin 50 nM.