TABLE 1.

Data Summary

Contracture	Total Motion (°)	Preoperative Extension (°)	Preoperative Flexion (°)	Myofibroblasts	Percent Myofibroblasts	Total Cells	α-SMA mRNA
Experimental	60	40	100	54	26	203	2.3
	58	32	90	52	22	242	2.4
	73	44	117	44	21	206	4.2
	85	38	123	27	20	134	3.4
	57	28	85	47	19	253	7.2
	15	75	90	57	20	285	5.5
	81	45	126	58	21	273	3.1
	74	34	108	29	10	279	2.0
Mean	63	42	105	46*	20‡	234	3.8†
SD	22	14	15	12	5	51	1.8
Control	> 130	—	—	18	10	182	2.0
	> 130	—	—	15	10	155	1.9
	> 130	—	—	18	10	191	3.2
	> 130	—	—	18	9	199	2.5
	> 130	—	—	21	11	188	1.8
	> 130	—	—	25	10	249	2.9
Mean	> 130	—	—	19*	10‡	194	2.4†
SD	—	—	—	3	1	31	0.6

Total motion = extension-flexion arc of motion; myofibroblasts = number of cells/field; percent myofibroblasts = myofibroblast numbers/total cell numbers; total cells = number of cells/field; α-SMA mRNA = optical density of scanned semiquantitative RT-PCR α-SMA/GAPDH mRNA expression; SD = standard deviation;

^*Significantly different at p < 0.0002;

^†Significantly different at p < 0.05;

^‡Significantly different at p < 0.05