Table 1.
Summary of EKG, Vm and Cai parameters under control and LQT2 conditions The asterix indicates that Cai lability was calculated from 2 beats preceding EAD onset, at the site of EAD origin.
| Parameter | Baseline | Dofetilide, before Ectopy | p |
|---|---|---|---|
| APD (ms) | 415±118 | 678±235 | p<0.01 |
| CaTD (ms) | 474±144 | 702±227 | p<0.005 |
| QT (ms) | 481±105 | 603±172 | p<0.05 |
| # of Cai peaks | 1.332±0.387 | 2.120±0.469 | p<0.002 |
| T wave lability | -4.061±0.944 | -2.894±0.950 | p<0.002 |
| AP lability | -3.436±0.492 | -2.994±0.779 | p<0.05 |
| Cai lability | -3.338± 0.372 | -2.970±0.647 | p=0.084 |
| Cai lability* | -4.049±0.685 | -3.356±1.033 | p<0.05 |
| Vm × Cai correlation | 0.9593±0.0231 | 0.8967±0.0644 | p<0.02 |