Skip to main content
. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Cell Res. 2010 Aug 10;20(11):1263–1275. doi: 10.1038/cr.2010.115

Figure 7. Transfected EphA3 induces growth cone collapse in lateral hippocampal neurons upon ephrin-A5 binding.

Figure 7

(A) Lateral hippocampal neurons were transfected with wild type or kinase-dead EphA3 plus GFP and treated with or without ephrin-A5. The growth cone morphology was examined under a Zeiss fluorescence microscope. Arrowheads indicate representative growth cones shown in inserts. Only transfected (GFP-positive) cells were included in the analysis. (B) Quantification of growth cone collapse in EphA3 mutant transfected lateral hippocampal neurons. Bars represent the means of at least 300 axons from three independent experiments; error bars indicate standard deviation. Asterisk * indicates α < 0.05 vs culture without ephrin-A5 treatment (one-way ANOVA followed with Bonferroni test for selected pairs).