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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Tissue Antigens. 2010 Aug 19;76(5):387–397. doi: 10.1111/j.1399-0039.2010.01526.x

Table 1.

Single marker analysis of HLA-Cw1, HLA-Cw6, and HLA-B46 associations with psoriasis in Thais and Caucasians

Allele Thais Caucasians
Frequency (proportion) in
 OR (95% CI)a Pb Frequency (proportion) in
 OR(95% CI)a Pb
cases controls cases controls
HLA-Cw1 94 (.2338) 26 (.1238) 2.16 (1.35, 3.46) 0.0011 161 (.0330) 182 (.0394) 0.83 (0.67, 1.03) 0.097
HLA-Cw6 71 (.1766) 9 (.0429) 4.79 (2.34, 9.80) 3.2 × 10−6 1139 (.2336) 420 (.0909) 3.05 (2.70, 3.44) 1.3 × 10−78
HLA-B46 79 (.1955) 22 (.0991) 2.21 (1.33, 3.66) 0.0017 0c (.0000) 0c (.0000) — —
a

Odds ratio and its 95% confidence interval for the allelic association test

b

P-value for allelic association test; multiallelic p-value for HLA-C is 3.4 × 10−8 in Thais and 3.2 × 10−77 in Caucasians

c

Frequency of HLA-B46 in Caucasians is based on typing all HLA-Cw1-positive individuals (160 cases and 174 controls successfully typed) and a large subsample of HLA-Cw1-negative individuals (505 cases and 667 controls successfully typed)