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Macrophage migration inhibitory factor (MIF; 20 ng/ml) promotes proliferation of Lewis lung carcinoma cells (**P = 0.02) relative to control. The proliferative response to MIF is inhibited in the presence of ISO-1 (pharmacologic MIF inhibitor), or antibody to the MIF cell surface receptor (CD74), but not CXCR2 or control IgG.
