Figure 6.

Effect of lenti–angiotensin (Ang)-(1–7) on right ventricular fibrosis. Pico Sirius red staining revealed increased collagen deposition (red) in the right ventricle of monocrotaline (MCT)-challenged rats, which was partially blocked by lenti–Ang-(1–7) administration. The beneficial effect of Ang-(1–7) was totally lost on coadministration of A-779, a Mas antagonist. Data are represented as mean ± SEM. *P < 0.05 versus control group, ^#P < 0.05 versus MCT, ^$P < 0.05 versus MCT + Ang-(1–7), (n = 3–5 per group).