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Summary of In Vivo Expression Results of wt and Sequence-Optimized Genes
| Cases of opt >wt (%) | Cases of opt = wt (%) | Cases of opt <wt (%) | No expression (%) | Ratio total expression (opt s wt, mean) | Ratio total expression (opt/wt, median) | |
|---|---|---|---|---|---|---|
| All genes (n = 94) | 54.3 | 3.2 | 20.2 | 22.3 | / | / |
| Expressible genes (n = 73) | 70.0 | 4.1 | 25.9 | / | 3.50 | 1.29 |
In total, 73 out of 94 constructs could be expressed in vivo.
