Table 2.
Initial and final water concentrations for (S)-mandelonitrile (3) synthesis in MTBE in the presence and absence of Na2HPO4⋅2 H2O/Na2HPO4⋅7 H2O.
| Salt kept during the reaction | Salt removed (standard conditions) | Control experiments | ||
|---|---|---|---|---|
| 1 | 2 | |||
| initial water concentration [ppm] | 3500[a] | 3200[a] | 4200[c] | 3100[d] |
| final water concentration [ppm] | 32 000[b] | 9600[b] | 5500[c] | 10 100[d] |
Measured after stirring the CLEA in the solvent for 1 h in the presence of the salt pair “2–7”.
Measured for the reaction mixture after 24 h.
The CLEA was stirred in the solvent in the presence of the salt pair “2-7” but without reagents for 24 h. The water concentration was measured after 1 h and after 24 h.
The reagents were stirred in the solvent in the presence of the salt pair “2-7” but without the CLEA. The water concentration was measured after 1 h and after 24 h.