Table 4.

Water concentrations and final (S)-mandelonitrile ee for reactions in octane.

	“Dry”	Sat.	0–2	2–7	7–12
water concentration of solvent [ppm]	40[a]	70[b]	–	–	–
water concentration of solvent + salt pair [ppm]	–	–	50[c]	50[c]	60[c]
initial water concentration of the reaction mixture [ppm]	50[d]	70[d]	10[e]	20[e]	50[e]
final water concentration of the reaction mixture [ppm][f]	50	80	50	40	60
final ee [%] of (S)-3	86	88	86	87	89

^[a]Measured for a sample of anhydrous solvent from Sigma–Aldrich.

^[b]Measured for a sample of water-saturated solvent.

^[c]In a separate experiment, the salt pairs were suspended in the anhydrous solvent and the system was stirred for 1 h before measuring the water concentration.

^[d]Measured after stirring the CLEA in the solvent for 1 h.

^[e]Measured after stirring the CLEA and the salt pair in the solvent for 1 h.

^[f]Measured for the reaction mixture after 24 h.