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This is a Kaplan-Meier plot of overall survival according to renal impairment (RI). P < .01 for patients with severe RI compared with patients with mild or no RI. RI was defined according to the creatinine clearance (CLCr) level as mild or no RI (CLCr ≥60 mL/minute), moderate RI (CLCr from ≥30 mL/minute to <60 mL/minute), or severe RI (CLCr <30 mL/minute).
