. Author manuscript; available in PMC: 2010 Nov 3.

Published in final edited form as: Exp Biol Med (Maywood). 2010 Aug 18;235(10):1263–1268. doi: 10.1258/ebm.2010.009376

Table 1.

Hemodynamic responses to smokeless tobacco

	Baseline	During ST			After ST

	0	10	20	30	40	50	60
HR (bpm)	67 ± 3	79 ± 3^*	77 ± 4^*	77 ± 4^*	74 ± 4^*	73 ± 4^**	71 ± 4
ED (ms)	292 ± 6	281 ± 5^*	280 ± 7^**	281 ± 6^*	285 ± 8	288 ± 8	290 ± 7
PSBP (mmHg)	124 ± 3	140 ± 6^*	141 ± 5^*	139 ± 5^*	136 ± 4^*	134 ± 4^*	129 ± 4^**
CSBP (mmHg)	109 ± 3	123 ± 5^*	124 ± 4^*	122 ± 4^*	120 ± 3^*	118 ± 3^*	115 ± 3^*
PDBP (mmHg)	79 ± 2	90 ± 4^*	90 ± 3^*	90 ± 3^*	88 ± 2^*	86 ± 2^*	84 ± 3^*
CDBP (mmHg)	80 ± 2	91 ± 4^*	92 ± 3^*	92 ± 3^*	89 ± 2^*	88 ± 3^*	85 ± 3^*
MAP (mmHg)	94 ± 3	106 ± 4^*	107 ± 3^*	106 ± 3^*	104 ± 3^*	102 ± 3^*	99 ± 3^*
P_i (mmHg)	106 ± 3	119 ± 5^*	119 ± 5^*	116 ± 5^*	116 ± 4^*	112 ± 4^*	109 ± 4
ESP (mmHg)	102 ± 3	114 ± 4^*	115 ± 4^*	114 ± 3^*	111 ± 3^*	110 ± 3^*	107 ± 3^**
AIx (%)	8.9 ± 2.2	7.1 ± 2.3	8.3 ± 2.6	8.7 ± 2.2	8.0 ± 2.4	9.2 ± 2.4	9.3 ± 2.5
AIx@75 (%)	4.1 ± 2.3	8.6 ± 2.1^*	8.5 ± 1.9^**	8.7 ± 1.9^*	6.8 ± 1.8	7.1 ± 2.3	7.0 ± 2.1
Δt_p (ms)	160 ± 3	150 ± 2^*	152 ± 2^*	149 ± 2^*	151 ± 2^*	149 ± 2^*	152 ± 3^*

P < 0.01,

^**

P < 0.05 versus respective baseline. Values reported as mean ± standard error of the mean. When significant within-subject variation was found, differences from baseline for each time point were determined using pairwise comparisons

HR, heart rate; ED, ejection duration; PSBP, peripheral systolic blood pressure; CSBP, central systolic blood pressure; PDBP, peripheral diastolic blood pressure; CDBP, central diastolic blood pressure; MAP, mean arterial pressure; P_i, central aortic pressure at inflection point