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. Author manuscript; available in PMC: 2011 Oct 9.
Published in final edited form as: Curr Opin Plant Biol. 2010 Oct 9;13(5):495–502. doi: 10.1016/j.pbi.2010.09.007

Figure 3. The tryptophan lock is part of a plant specific recognition loop in clade A PP2Cs.

Figure 3

ABI1 and HAB1 dock onto PYR/PYL proteins and insert their conserved tryptophan lock residues between the gate and latch. This recognition module is absent from human PP2C structures and therefore a plant specific modulation of PP2C. Eight of the 9 clade A PP2Cs contain the tryptophan lock residue and it is absent from other plant PP2Cs.