Table 3.
Association between NAT1*10 and risk of NHL and NHL Subtypes
| No NAT1*10 alleles | Heterozygous for NAT1*10 | NAT1*10/*10 | Heterozygous for NAT1*10 or NAT1*10/*10 | |||||
|---|---|---|---|---|---|---|---|---|
| n | OR (95%CI) | n | OR (95%CI) | n | OR (95%CI) | n | OR (95%CI) | |
| Controls | 328 | 172 | 22 | 194 | ||||
| All NHL | 289 | 1.0 | 145 | 1.0 (0.7–1.3) | 19 | 1.1 (0.6–2.0) | 164 | 1.0 (0.7–1.3) |
| Subtype | ||||||||
| DBCL | 104 | 1.0 | 36 | 0.7 (0.4–1.0) | 4 | 0.6 (0.2–1.9) | 40 | 0.7 (0.4–1.0) |
| Follicular | 69 | 1.0 | 33 | 0.9 (0.6–1.5) | 4 | 1.0 (0.3–3.1) | 37 | 0.9 (0.6–1.4) |
| SLL/CLL | 32 | 1.0 | 20 | 1.2 (0.7–2.2) | 2 | 1.0 (0.2–4.3) | 22 | 1.2 (0.7–2.1) |
| Marginal | 19 | 1.0 | 10 | 1.0 (0.4–2.2) | 1 | 0.9 (0.1–6.8) | 11 | 1.0 (0.4–2.1) |
| T-Cell | 15 | 1.0 | 17 | 2.2 (1.1–4.5) | 1 | 1.0 (0.1–8.0) | 18 | 2.0 (1.0–4.2) |
†
DLBCL=Diffuse large B-cell lymphoma; SLL/CLL=small lymphocytic lymphoma/chronic lymphocytic leukemia;
‡
Odds Ratio (OR) [95% confidence interval (CI)] adjusted for age, race, and family history of NHL