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. 2010 Nov 3;5(11):e13797. doi: 10.1371/journal.pone.0013797

Table 1. Outcome of antiviral epidemic measures with various diagnosis delays and coverages.

final symptomatic attack rate (%) peak daily incidence (per 10,000)
baseline 24.5 109
intervention strategy diagnosis delay diagnosis coverage diagnosis delay diagnosis coverage
0 h 24 h 48 h 10% 50% 90% 0 h 24 h 48 h 10% 50% 90%
T 17.4 21.0 22.4 23.8 21.0 17.8 63 84 96 104 84 68
T+SC 13.6 17.1 18.2 18.4 17.1 14.5 29 39 41 48 39 35
T+H 12.2 16.5 18.4 22.9 16.5 11.1 33 56 69 95 56 30
T+H+SC 8.7 13.0 15.0 17.6 13.0 7.8 16 27 31 43 27 15
T+H+E 8.8 13.0 15.4 20.8 13.0 7.6 20 34 47 84 34 17
T+H+E+SC 6.7 10.7 13.4 16.8 10.7 6.1 12 19 26 39 19 12

Final symptomatic attack rate (as % of population) and peak daily symptomatic incidence (per 10,000) are given for different intervention strategies, diagnosis delays and diagnosis coverages. Intervention strategies are abbreviated as follows: T – antiviral treatment of diagnosed cases, H – prophylaxis of household of diagnosed cases, E – prophylaxis of school or work contacts of diagnosed cases, SC – four weeks of school closure. Where diagnosis delay differs from 24 hours, diagnosis coverage is 50%; where diagnosis coverage differs from 50%, diagnosis delay is 24 hours.