Skip to main content
. 2010 Oct 12;11:506. doi: 10.1186/1471-2105-11-506

Figure 7.

Figure 7

microRNA Analysis I. The output of a Geoseq query run on sRNA-Seq libraries. In the Starts view, the histogram displays the number of times the k-mer starting at a position was found in the library (there is one histogram per user-selected library). In the Coverage view, the numbers represent the sum of contributions for each tile that covers the position. This figure shows the results of miRNA, dme-mir-10 queried against two D. melanogaster libraries, SRR001664 and SRR001343. The tracks below the histograms indicate the positions of known mature and star sequences for mir-10 according to miRBase [8]. Below this is shown the folded structure of the pre-miRNA from RNAfold [15]. In experiment SRR001664, the expression of the mature sequence is greater than the expression of the star, which is the canonical case. However, in library SRR001343, the expression of the canonical star-sequence is similar to the expression of the mature sequence. This suggests that the roles of star and mature sequences may, on occasions, be context-dependent.