Table 1.
Approximate genus level: 95% similarity to closest cultured relative | Phyla | % of all BB-DP reads | % of all BB-DR reads | P-value | Fold difference |
---|---|---|---|---|---|
Bacteroides | Bacteroidetes | 6.732 | 6.101 | 2.00E–05 | 1.5 |
Bifidobacterium | Actinobacteria | 0.041 | 0.940 | 2.00E−05 | 16.8 |
Eubacterium | Firmicutes | 4.009 | 2.050 | 2.00E−05 | 2.6 |
Halothermothrix | Firmicutes | 0.126 | 0.003 | 2.00E−05 | 55.0 |
Lactobacillus | Firmicutes | 5.320 | 8.012 | 2.00E−05 | 1.1 |
Prevotella | Bacteroidetes | 0.307 | 0.630 | 2.00E−05 | 1.5 |
Pseudobutyrivibrio | Firmicutes | 0.112 | 0.453 | 2.00E−05 | 3.0 |
Ruminococcus | Firmicutes | 2.302 | 1.675 | 2.00E−05 | 1.9 |
Spiroplasma | Mollicutes | 0.000 | 0.112 | 2.00E−05 | 36 |
Anaerostipes | Firmicutes | 0.127 | 0.0523 | 0.000680 | 3.2 |
Mucispirillum | Deferribacteres | 0.224 | 0.130 | 0.000760 | 2.3 |
Butyrivibrio | Firmicutes | 0.030 | 0.000 | 0.000980 | 13 |
Proteiniphilum | Bacteroidetes | 0.062 | 0.143 | 0.001420 | 1.7 |
Streptococcus | Firmicutes | 0.025 | 0.081 | 0.001700 | 2.4 |
Turicibacter | Firmicutes | 0.654 | 0.909 | 0.002040 | 1.2 |
Pediococcus | Firmicutes | 0.032 | 0.003 | 0.003080 | 14 |
Sporobacter | Firmicutes | 1.396 | 1.262 | 0.007040 | 1.5 |
Bryantella | Firmicutes | 0.838 | 1.089 | 0.009580 | 1.4 |
% of total reads | 22.334 | 23.645 |
Abbreviations: BB-DP, bio-breeding diabetes-prone; BB-DR, bio-breeding diabetes-resistant.
The percent of total reads is shown for each genus. Those percent of read numbers in bold indicate the genotype (BB-DP or BB-DR), which is higher for that genus. Here a 16S rRNA sequence is considered to be derived from a known genus if it is at a similarity level of 95% or above to its closest cultured relative.