Table 2. Change in mean arterial blood pressure (MAP) and cerebral blood flow (CBF).
MAP mm Hg | gCBF mL per 100 g per minute | BZ mL per 100 g per minute | leuko mL per 100 g per minute | PIB mL per 100 g per minute | |
---|---|---|---|---|---|
Baseline | 107.0±12.6 | 43.5±11.1 | 42.0±11.3 | 20.9±7.2 | 58.8±16.0 |
Postnicardipine | 92.3±9.1 | 42.5±9.7 | 40.0±9.9 | 20.6±7.0 | 56.2±17.4 |
% Changea | −13.5%±3.3% | −0.6%±12.8% | −3.2%±12.1% | 1.2%±22.0% | −4.5%±12.8% |
BZ, borderzone regions; g, global; leuko, regions of leukoaraiosis (differences computed in the eight subjects with ARIC leukoaraiosis scores (Wong et al, 2002) of ⩾5); PIB, regions of peak PIB uptake (differences computed in the 11 subjects in whom peaks comprised at least 10 mL).
Percentage change calculated as the mean of the percent change in values for each subject.