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. Author manuscript; available in PMC: 2011 Nov 19.
Published in final edited form as: J Mol Biol. 2010 Sep 8;404(1):45–55. doi: 10.1016/j.jmb.2010.08.054

Figure 1.

Figure 1

A) Structure of ASIP (in blue) and AgRP (in red), and identification of the three loops interchanged in chimera constructs. Disulfide bonds are shown in yellow. B) The sequences of AgRP (above) and ASIP (below) showing disulfide connectivities and the delineation of the three interchanged regions.