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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Pain. 2010 Dec;151(3):625–632. doi: 10.1016/j.pain.2010.08.002

Table 4.

Medical and Psychiatric Diagnoses in the Past Five Years.

High-Dose
Opioid
Group
(n=478)
Traditional-
Dose Opioid
Group
(n=500)
No Opioid
Group
(n=500)
Test (df) p-value
Medical Diagnoses

Hypertension 298 (62.3%) 346 (69.2%) 292 (58.4%) χ2 (2) = 12.9 0.002
Congestive Heart 59 (12.3%) 43 (8.6%) 32 (6.4%) χ2 (2) = 10.7 0.005
Failure
Myocardial Infarction 34 (7.1%) 32 (6.4%) 21 (4.2%) χ2 (2) = 4.1 0.13
Diabetes 151 (31.6%) 129 (25.8%) 133 (26.6%) χ2 (2) = 4.8 0.09
Sleep Apnea 97 (20.3%) 96 (19.2%) 82 (16.4%) χ2 (2) = 2.6 0.27
Cerebrovascular 57 (11.9%) 51 (10.2%) 51 (10.2%) χ2 (2) = 1.0 0.61
Disease
Peripheral Vascular 55 (11.5%) 45 (9.0%) 38 (7.6%) χ2 (2) = 4.5 0.11
Disease
Chronic Pulmonary 176 (36.8%) 175 (35.0%) 146 (29.2%) χ2 (2) = 7.0 0.03
Disease
Paraplegia and/or 26 (5.4%) 16 (3.2%) 11 (2.2%) χ2 (2) = 7.7 0.02
Hemiplegia

Psychiatric Diagnoses

Major Depressive 320 (66.9%) 303 (60.6%) 200 (40.0%) χ2 (2) = 79.3 < 0.001
Disorder
Dysthymic Disorder 87 (18.2%) 62 (12.4%) 50 (10.0%) χ2 (2) = 14.8 0.001
Bipolar Disorder 28 (5.9%) 45 (9.0%) 42 (8.4%) χ2 (2) = 3.8 0.15
Panic Disorder 33 (6.9%) 35 (7.0%) 15 (3.0%) χ2 (2) = 9.8 0.008
Posttraumatic Stress 179 (37.4%) 169 (33.8%) 134 (26.8%) χ2 (2) = 13.1 0.001
Disorder
Other Anxiety Disorder 122 (25.5%) 122 (24.4%) 79 (15.8%) χ2 (2) = 16.4 < 0.001
Schizophrenia 13 (2.7%) 24 (4.8%) 18 (3.6%) χ2 (2) = 3.0 0.23
Any Sleep Disorder 103 (21.5%) 102 (20.4%) 64 (12.8%) χ2 (2) = 15.2 0.001
Any Alcohol or 175 (36.6%) 165 (33.0%) 114 (22.8%) χ2 (2) = 23.8 < 0.001
Substance Use Disorder
Nicotine Disorder 172 (36.0%) 157 (31.4%) 99 (19.8%) χ2 (2) = 33.3 < 0.001

Past-Year Charlson
Comorbidity Score,
Mean (SD)
1.2 (1.6)a 1.0 (1.5)a,b 0.9 (1.4)b F (2, 1477) =
5.2
0.006

Note. Scores with different superscripts differed significantly (p < 0.05) in post-hoc testing.