Figure 2.

Caveolaelike structures in corneal epithelium from young, middle-aged and elderly patients. (A) Caveolaelike structures in corneal epithelia of one young (Y4, age 20 years), one middle-aged (M12, age 45 years), and one elderly (E20, age 70 years) patient were visualized by using electron microscopic analysis. The arrow indicates caveolae structures. Bar = 100 nm. (B) The number of caveolaelike vesicles in the corneal epithelium of the three age groups were counted and plotted as a histogram with mean ± SD. Significant differences between young and middle-aged or elderly patients are indicated with asterisks (**P < 0.01, and ***P < 0.001).