Table 3.
Paired analysis for surrogate parameters of hepatic encephalopathy in nine individual patients who were assessed before and after liver transplantation. (pNH3 was only available for three patients). Differences between groups were tested for statistical significance by Student’s t-test or the Wilcoxon test for paired samples
| Patients with liver cirrhosis median (95% CI) | Patients after liver transplantation median (95% CI) | Mean difference before and after LT (95% CI) | Significance | ||
|---|---|---|---|---|---|
| pNH3× 10−5 mmHg | 6.0 (3.3–8.1) | 1.6 (1.3–2.1) | −3.96 (−1.89– −6.4) | 0.014 | |
| PSE test | −10.0 (−15.9–3.4) | −10.0 (−20.0–5.9) | 5.00 (−8.2– −1.9) | 0.006 | |
| Median CFF [Hz] | 34.6 (12.4–55.5) | 44.8 (4.8–77.4) | 3.96 (−9.3– −1.33) | 0.123 | |
| LATER parameters | μ | 2.8 (1.8–4.4) | 4.0 (2.3–5.2) | 0.13 (0.67– −0.41) | 0.602 |
| σ | 1.1 (0.3–1.6) | 1.0 (0.9–1.1) | −0.04 (0.42– −0.50) | 0.841 | |
| σ E | 3.4 (−4.3–10.5) | 4.1 (−3.1–8.6) | 0.47 (2.5– −1.56) | 0.607 | |