Figure 2.

Cooperative recruitment of cortical neurons in response to stimulation of distinct olfactory bulb glomeruli. Sequential imaging of peak dF/F responses to stimulation in the olfactory bulb glomerular layer (top) and cell activity maps in piriform cortex (bottom) are shown. A, Focal stimulation in one glomerular region (Stim1) activates an ensemble of cells in cortex (red). B, Focal stimulation of a different glomerular region (Stim2) activates another ensemble of cells (green) some of which were also activated by Stim1 (open circles are cells from A). C, Simultaneous stimulation of the two glomerular regions (Stim1 + 2) recruits a large ensemble of cells that were not activated by each pathway alone (black cells). Scale bar, 100 μm.