Table 3.

Infarct size assessed by single-photon emission computed tomography in patients presenting with STEMI and treated by revascularization alone or in conjunction with endovascular cooling in the COOL-MI⁸ and the ICE-IT¹⁰ studies

	Infarct size (% left ventricle)		P-value
	Cooled group	Normothermic group
COOL-MI (n = 392 patients)
Overall population	13.8	14.1	0.86
Subgroup with anterior STEMI cooled to <35°C at the time of revascularization	9.3	18.2	0.05
ICE-IT (n = 228 patients)
Overall population	10.2	13.2	0.14
Subgroup with anterior STEMI cooled to <35°C at the time of revascularization	12.9	22.7	0.09

STEMI, ST-segment elevation myocardial infarction.

Data were obtained from Holzer and Behringer⁴¹, Polderman⁸³ and Wolfrum et al.⁸⁴